Interaction between DRD2 and AKT1 genetic variations on risk of psychosis in cannabis users: a case–control study
nasli spojitost medzi rizikovymi alelami dvoch genov a konzumaciou marihuany.
Our results indicate a model of interaction known as ‘qualitative G×E interaction’ with a crossover pattern: carriers of risk allele(s) for one of the two genes (DRD2 rs1076560 T or AKT1 rs2494732 C allele), compared with individuals carrying no ‘risk’ alleles (DRD2 rs1076560 GG/AKT1 rs2494732 TT), have a lower probability of psychotic disorder if they never used cannabis but a higher probability if they have a history of cannabis use, especially of daily use.
Y os je odds ratio
Embrace The Void!